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KMID : 1201420170100020126
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Journal of Neurocritical Care
2017 Volume.10 No. 2 p.126 ~ p.128
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Glanzmann Thrombasthenia in a Korean Patient: A Postoperative Intracranial Hemorrhagic Diasthesis in a Patient with a Rupture of a Cerebral Aneurysm
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Choi Mi-Sun
Lee Joo-Hee
Lim Yong-Cheol
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Abstract
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Background: Glanzmann thrombasthenia (GT) is a rare disease with severe insufficiency of platelet function. There are no reports of GT associated with a cerebral hemorrhage.
Case report: A 45-year-old woman had a stuporous mentality. Her computed tomographic (CT) angiography revealed a rupture of the posterior cerebral artery aneurysm. Hunt-Hess grade was 4 points and Fisher grade was 3 points. A clipping of the aneurysm was performed and proceeded to external ventricular drainage for hydrocephalus after 6 days. But, a new hemorrhage was detected several times via a follow-up brain CT. Various blood tests were conducted to evaluate the bleeding tendency, and the GT was diagnosed with PFA-200. The ventriculoperitoneal shunt was performed after the platelets transfusion, and she was discharged without other complications.
Conclusions: With nonspecific and recurrent intracranial hemorrhage, a GT shou ld be included in the differential diagnosis, which is important in controlling bleeding during the surgery.
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KEYWORD
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Trombasthenia, Postoperative hemorrhages, Aneurysm, Ruptured
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